High-definition visualization using approximately
237,000 electrodes

 High-density CMOS-MEA system

High-density CMOS-MEA system

Features

This system enables high-density measurements of a cell’s electrical activity, which was previously difficult.
It makes possible real-time data recording and visualization as well as analysis at the single-cell level.
This technology offers new solutions for drug discovery and the neuroscience field, and moreover for basic research in areas such as neurological disorders.

This high-density CMOS-MEA equipped with approximately 237,000 electrodes and image sensor technologies is capable of measuring electrical activity at the single-cell level. For comparison, a conventional MEA equipped with 16 to 64 electrodes can observe only mass potentials from multiple cells.

Offer for test users

To request the free rental of equipment, contact us through the rental form provided above. A representative will contact you shortly.

SCREEN Holdings Co., Ltd., Sony Semiconductor Solutions Corporation, and VitroVo, Inc. have jointly developed a high-density CMOS-MEA system.

We are offering test users the opportunity to verify the efficacy of the system and evaluation method.

Optimizes tasks from measurement to analysis with simple operations

The measurement and analysis software was developed based on the elemental technology of the SCREEN Group’s extracellular electrophysiological measurement system “MED64.”
It supports the smooth implementation of trials and research by analyzing and visualizing cellular action potentials in real time.
The system makes it possible to output the analysis results by a simple operation and to display a list of characteristics of parameter units for multiple recording data.

Example application: glutamatergic neurons

Glutamatergic neurons can be cultured on the CMOS-MEA to measure their spontaneous activity.
The number of spikes and a raster plot can be displayed in real time.
This enables the evaluation of responses to chemical compounds and electrical stimulation.

Advanced analysis support (VitroVo, Inc.)

Users can send their measurement data to VitroVo for analysis. We support research and development, including by evaluating the efficacy and toxicity of compounds by analyzing data sent by users, such as the firing patterns of a single cell and synaptic transmission strength, using methods that include network analysis, axonal conduction velocity analysis, and frequency analysis.